rct
2021
High Quality
Nattokinase atherothrombotic prevention study: a randomized controlled trial
Hodis HN, Mack WJ, Meiselman HJ
Published in Clinical Hemorheology and Microcirculation, Vol. 78 (4), pp. 339-353
Key Findings
Nattokinase did not change carotid intima-media thickness progression or fibrinolytic and coagulation markers versus placebo over one year.
Conclusions
Rigorous null result against the atherosclerosis claims.
Limitations
Single centre, one-year follow-up.
Supplements Studied
Nattokinase
Enzyme
Nattokinase did not change carotid intima-media thickness progression or coagulation markers versus placebo over one year.
Outcomes Measured
there was no significant effect of nattokinase supplementation on blood pressure or any laboratory determination
Related Health Concerns
Study Details
Year:2021
Sample Size:265
Duration:52 weeks
Quality Score:8/10
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