Multivitamins in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial
Sesso HD, Christen WG, Bubes V, Smith JP, MacFadyen J, Schvartz M
Published in JAMA, Vol. 308 (17), pp. 1751-60
Methodology
Large randomized double-blind placebo-controlled trial of a daily multivitamin in male physicians over more than a decade of follow-up.
Key Findings
The multivitamin produced a small reduction in total cancer incidence but no reduction in major cardiovascular events or mortality.
Conclusions
Daily multivitamins do not prevent cardiovascular disease despite improving nutrient adequacy.
Limitations
Well-nourished male physicians; results may not generalise.
Supplements Studied
The multivitamin produced no reduction in major cardiovascular events or mortality
Outcomes Measured
The multivitamin produced a small reduction in total cancer incidence but no reduction in major cardiovascular events or mortality
Related Health Concerns
Study Details
Access Study
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.