The effectiveness of leucine on muscle protein synthesis, lean body mass and leg lean mass accretion in older people: a systematic review and meta-analysis
Xu ZR, Tan ZJ, Zhang Q, Gui QF, Yang YM
Published in British Journal of Nutrition, Vol. 113 (1), pp. 25-34
Methodology
Meta-analysis of randomised trials of leucine supplementation on muscle protein synthesis rate and lean mass in older adults.
Key Findings
Leucine significantly increased muscle protein synthesis rate but did not consistently increase lean body mass or strength.
Conclusions
Leucine acutely stimulates protein metabolism without reliable long-term mass gains.
Limitations
Short trial durations; synthesis is a surrogate outcome.
Supplements Studied
Leucine significantly increased muscle protein synthesis rate but did not consistently increase lean body mass
Outcomes Measured
Leucine significantly increased muscle protein synthesis rate but did not consistently increase lean body mass or strength
Leucine significantly increased muscle protein synthesis rate but did not consistently increase lean body mass or strength.
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.