Intake of omega-3 polyunsaturated fatty acids in patients with rheumatoid arthritis: a systematic review and meta-analysis
Gioxari A, Kaliora AC, Marantidou F
Published in Nutrition, Vol. 45, pp. 114-124.e4
Methodology
Systematic review and meta-analysis of 20 RCTs of marine omega-3 in rheumatoid arthritis.
Key Findings
Omega-3 modestly reduced tender joint count, morning stiffness and NSAID use; effects on inflammatory markers were inconsistent.
Conclusions
Marine omega-3 is a reasonable adjunct for symptom control in rheumatoid arthritis, not a disease-modifying therapy.
Limitations
Small heterogeneous trials, varied doses and durations, open-label components.
Supplements Studied
Omega-3 modestly reduced tender joint count and NSAID use in rheumatoid arthritis.
Outcomes Measured
Omega-3 modestly improved rheumatoid arthritis symptom measures.
Related Health Concerns
Study Details
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