systematic_review
    2017
    High Quality

    The role of flower pollen extract in managing patients affected by chronic prostatitis/chronic pelvic pain syndrome: a comprehensive analysis of all published clinical trials

    Cai T, Verze P, La Rocca R, Anceschi U, De Nunzio C, Mirone V

    Published in BMC Urol, Vol. 17 (1), pp. 32

    Methodology

    Systematic review of PubMed and Embase to June 2016 of preclinical and clinical studies of flower pollen extract in CP/CPPS, with a meta-analysis of randomised trials.

    Key Findings

    Six uncontrolled studies (206 patients) had a mean response rate of 83.6%; four RCTs included 384 patients. Pooled, the extract improved quality of life (OR 0.52, 0.34-0.81; p=0.02). No significant adverse events were reported.

    Conclusions

    Flower pollen extract appears beneficial in CP/CPPS; more robust RCTs with longer follow-up are needed.

    Limitations

    Few, small and heterogeneous trials of different products; authors ran several of the included trials; uncontrolled response rates are inflated by placebo response.

    Supplements Studied

    flower pollen extract could significantly improve patients' quality of life

    Related Health Concerns

    Study Details

    Year:2017
    Quality Score:7/10

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