Effects of a fish oil enriched diet on aspirin intolerant asthmatic patients: a pilot study
Picado C, Castillo JA, Schinca N, Pujades M, Ordinas A, Coronas A, et al.
Published in Thorax, Vol. 43 (2), pp. 93-97
Methodology
Single-blind pilot in 10 people with aspirin-intolerant asthma: six weeks on a control diet followed by six weeks on a fish-oil-enriched diet providing about 3 g/day of EPA, with twice-daily peak flow, medication use and symptom diaries.
Key Findings
Symptom scores did not change. In weeks five and six of the fish oil diet, peak expiratory flow was lower (262 vs 308 L/min and 256 vs 306 L/min) and bronchodilator use was higher (12.0 vs 7.4 and 13.0 vs 7.4 puffs/day) than during the control diet.
Conclusions
The authors suggested fish diets may have a harmful effect in aspirin-intolerant asthma.
Limitations
Ten participants, no randomisation or crossover, diet order not varied, and sinus outcomes were not measured. Relevant to chronic sinusitis only through aspirin-exacerbated respiratory disease, which includes nasal polyps.
Supplements Studied
fish diets may have a deleterious effect on patients with aspirin intolerant asthma
Related Health Concerns
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.