Remedy Routes
    rct
    1998
    High Quality

    Finasteride in the treatment of men with androgenetic alopecia

    Kaufman KD, Olsen EA, Whiting D, Savin R, DeVillez R, Bergfeld W, et al.

    Published in Journal of the American Academy of Dermatology

    Key Findings

    Finasteride 1 mg/day inhibited type II 5-alpha-reductase, lowered scalp and serum DHT, and increased hair counts versus placebo over two years.

    Conclusions

    5-alpha reductase inhibition durably reverses androgen-driven follicular miniaturization.

    Limitations

    Pharmaceutical drug rather than supplement; industry funded.

    Outcomes Measured

    5-Alpha Reductase Inhibition
    Primary

    Finasteride, an inhibitor of type II 5alpha-reductase, decreases serum and scalp DHT by inhibiting conversion of testosterone to DHT.

    Study Details

    Year:1998
    Sample Size:1,553
    Duration:104 weeks
    Quality Score:8/10

    Access Study

    View on DOIView on PubMedOriginal Source

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