Comparative Assessment of Efficacy and Safety of Approved Oral Therapies for Overactive Bladder: A Systematic Review and Network Meta-Analysis
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Published in Not fully verifiable
Abstract
This study evaluated the comparative efficacy and safety of approved oral therapies for overactive bladder based on a systematic review and network meta-analysis.
Methodology
Network meta-analysis of RCTs comparing approved OAB oral therapies for efficacy and safety.
Key Findings
Both antimuscarinic agents and beta-3 adrenergic agonists demonstrated efficacy over placebo; mirabegron showed a more favorable tolerability profile.
Conclusions
Multiple oral therapy classes are effective for OAB; treatment selection should weigh comparative safety profiles.
Limitations
Details not independently verifiable beyond abstract; indirect comparison limitations; potential heterogeneity.
Related Health Concerns
Study Details
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