Effect of Dietary Interventions on Endometriosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meneghetti JK, Pedrotti MT, Coimbra IM, da Cunha-Filho JSL
Published in Reproductive Sciences
Methodology
Systematic review of 11 RCTs (716 women) with meta-analysis of 6 RCTs (457 women) on dietary and supplement interventions in endometriosis
Key Findings
Antioxidant supplementation reduced dysmenorrhea (MD -1.95, 95% CI -3.78 to -0.13) but did not significantly reduce chronic pelvic pain (MD -2.22, 95% CI -4.99 to 0.55).
Conclusions
Dietary and antioxidant interventions show a modest benefit for dysmenorrhea but not for chronic pelvic pain in endometriosis.
Limitations
Most included trials had moderate or high risk of bias and interventions were heterogeneous.
Supplements Studied
antioxidant use was associated with a reduction in dysmenorrhea (mean difference - 1.95 [CI 95%, -3.78 to -0.13]
Related Health Concerns
Study Details
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Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.