systematic_review
    2017

    Role of guaifenesin in the management of chronic bronchitis and upper respiratory tract infections

    Albrecht HH, Dicpinigaitis PV, Guenin EP

    Published in Multidisciplinary Respiratory Medicine

    Methodology

    Review of clinical trials of guaifenesin as an expectorant in acute and chronic airway congestion.

    Key Findings

    Guaifenesin reduced sputum thickness and cough frequency in several small trials, with limited effect on objective mucus clearance.

    Conclusions

    Guaifenesin offers modest symptomatic relief of chest congestion, not disease modification.

    Limitations

    Small, older trials; manufacturer-affiliated authors; subjective endpoints.

    Outcomes Measured

    Respiratory Health

    Guaifenesin reduced sputum thickness and cough frequency in several small trials.

    Related Health Concerns

    Chronic Bronchitis
    Chest Congestion
    Cough

    Study Details

    Year:2017
    Sample Size:1,000
    Quality Score:5/10

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