A systematic review on botany, ethnopharmacology, quality control, phytochemistry, pharmacology and toxicity of Arctium lappa L. fruit
Jin X, Liu S, Chen S, Wang L, Cui Y
Published in Journal of Ethnopharmacology
Methodology
Systematic review of botanical, phytochemical, pharmacological and toxicological literature on Arctii Fructus across multiple databases and pharmacopoeias.
Key Findings
More than 200 compounds have been identified, mainly lignans (arctiin, arctigenin), phenolic acids and terpenoids, with anti-inflammatory, antioxidant, antidiabetic and antitumour activity reported almost entirely in preclinical models.
Conclusions
Arctium lappa contains well-characterised bioactive lignans, but supporting pharmacology is preclinical and clinical confirmation is lacking.
Limitations
Reviews fruit rather than root, dominated by in vitro and animal data, no meta-analysis of human outcomes.
Supplements Studied
To date, more than 200 compounds have been isolated and identified from Arctii Fructus.
Study Details
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Disclosures
Funding
Not clearly stated
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