meta_analysis
    2018
    High Quality

    Micronized purified flavonoid fraction in chronic venous disease: systematic review and meta-analysis

    Kakkos SK, Nicolaides AN

    Published in International Angiology

    Methodology

    Meta-analysis of randomized trials of diosmin-hesperidin flavonoid fraction on venous symptoms, oedema and quality of life.

    Key Findings

    Flavonoid fraction significantly reduced leg oedema, heaviness, cramps and improved quality of life versus placebo or control.

    Conclusions

    Diosmin-based flavonoids improve venous return symptoms.

    Limitations

    Industry-sponsored trials predominate.

    Outcomes Measured

    Venous Return

    Flavonoid fraction significantly reduced leg oedema, heaviness, cramps and improved quality of life versus placebo

    Study Details

    Year:2018
    Duration:24 weeks
    Quality Score:7/10

    Access Study

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