Effect of conjugated linoleic acid on body fat accretion in overweight or obese children
Racine NM, Watras AC, Carrel AL, Allen DB
Published in The American Journal of Clinical Nutrition
Methodology
7-month randomized double-blind placebo-controlled trial of 3 g/day 80% CLA versus placebo in chocolate milk, with DXA body composition
Key Findings
CLA attenuated BMI gain and reduced percentage body fat and abdominal fat versus placebo, but HDL cholesterol fell more and bone mineral accretion was lower in the CLA group.
Conclusions
CLA modestly reduced fat accretion in children but with unfavourable HDL and bone effects.
Limitations
Paediatric population limits generalisability to adults, small sample, adverse lipid and bone signals.
Outcomes Measured
The change in abdominal body fat as a percentage of total body weight was smaller (P = 0.02) in the CLA group (-0.09 +/- 0.9%) than in the placebo group (0.43 +/- 0.6%).
Study Details
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Disclosures
Funding
NIH extramural support
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