Hair growth promotion activity and its mechanism of Polygonum multiflorum
Li Y, Han M, Lin P, He Y, Yu J
Published in Evidence-Based Complementary and Alternative Medicine
Methodology
Controlled animal experiment in C57BL/6J mice comparing raw and processed Polygonum multiflorum Radix on hair length, follicle number, skin coverage and growth-factor signalling (FGF-7, SHH, beta-catenin, IGF-1, HGF)
Key Findings
Oral raw root promoted hair growth in mice via growth-factor signalling; no human data support the traditional hair-loss claim.
Conclusions
Hair-growth evidence for Fo-Ti remains entirely preclinical.
Limitations
Mouse model; oral crude extracts; no clinical endpoints.
Supplements Studied
However, several crucial problems in its clinic usage and mechanisms are still unsolved or lack scientific evidences.
Related Health Concerns
Study Details
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Disclosures
Funding
Not reported
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