cohort
    2010
    High Quality

    Marine omega-3 fatty acids and prospective change in leukocyte telomere length: the Heart and Soul Study

    Farzaneh-Far R, Lin J, Epel ES, Harris WS, Blackburn EH, Whooley MA

    Published in JAMA

    Methodology

    Prospective cohort of patients with stable coronary artery disease relating baseline omega-3 blood levels to five-year change in leukocyte telomere length.

    Key Findings

    Higher baseline DHA and EPA levels predicted significantly slower telomere shortening over five years in a dose-response manner.

    Conclusions

    Omega-3 status is associated with slower telomere attrition.

    Limitations

    Observational; single clinical population.

    Supplements Studied

    Higher baseline DHA and EPA levels predicted significantly slower telomere shortening over five years

    Outcomes Measured

    Higher baseline DHA and EPA levels predicted significantly slower telomere shortening over five years in a dose-response manner

    Study Details

    Year:2010
    Sample Size:608
    Duration:260 weeks
    Quality Score:7/10

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