rct
    1998
    High Quality

    Finasteride in the treatment of men with androgenetic alopecia

    Unknown authors

    Published in Journal of the American Academy of Dermatology

    Key Findings

    Finasteride 1 mg/day inhibited type II 5-alpha-reductase, lowered scalp and serum DHT, and increased hair counts versus placebo over two years.

    Conclusions

    5-alpha reductase inhibition durably reverses androgen-driven follicular miniaturization.

    Limitations

    Pharmaceutical drug rather than supplement; industry funded.

    Outcomes Measured

    5-Alpha Reductase Inhibition
    Primary

    Finasteride, an inhibitor of type II 5alpha-reductase, decreases serum and scalp DHT by inhibiting conversion of testosterone to DHT.

    Study Details

    Year:1998
    Sample Size:1,553
    Duration:104 weeks
    Quality Score:8/10

    Access Study

    View on DOIView on PubMedOriginal Source

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