Efficacy and Safety of GutGard in Managing Gastroesophageal Reflux-Related Symptoms: A Phase III, Single-Centre, Double-Blind, Randomized Placebo-Controlled Trial
Raj JP, Saxena U, Belhekar MN, Mamde A, Darak H, Pawar S
Published in Complementary Medicine Research
Methodology
Phase III single-centre double-blind randomized placebo-controlled trial of a standardised deglycyrrhizinated licorice extract in patients with GERD-related symptoms
Key Findings
The licorice extract significantly reduced heartburn and other GERD-related symptom scores versus placebo with good tolerability
Conclusions
A standardised licorice root extract may be a safe, effective option for GERD-related symptoms
Limitations
Single-centre; proprietary manufacturer-linked extract; short duration
Supplements Studied
GutGard significantly improved gastroesophageal reflux-related symptoms compared with placebo.
Related Health Concerns
Study Details
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Disclosures
Funding
Manufacturer of the proprietary extract
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