systematic_review
    2004

    Pyridoxine hydrochloride treatment of carpal tunnel syndrome: a review

    Aufiero E, Stitik TP, Foye PM

    Published in Nutrition Reviews

    Methodology

    Review of controlled and uncontrolled studies of vitamin B6 for carpal tunnel syndrome.

    Key Findings

    Evidence is conflicting; some studies report symptom relief while controlled trials show no advantage over placebo, and high doses risk sensory neuropathy.

    Conclusions

    Vitamin B6 is not established therapy for carpal tunnel syndrome and carries neuropathy risk above 200 mg/day.

    Limitations

    Narrative synthesis of heterogeneous, mostly older studies.

    Outcomes Measured

    Nerve Health

    High-dose vitamin B6 above 200 mg/day risks sensory neuropathy.

    Related Health Concerns

    Carpal Tunnel Syndrome

    Study Details

    Year:2004
    Sample Size:500
    Quality Score:5/10

    Access Study

    View on PubMedOriginal Source

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