Resveratrol supplementation and lifespan or healthspan markers in humans: a systematic review
Berman AY, Motechin RA, Wiesenfeld MY, Holz MK
Published in npj Precision Oncology
Methodology
Systematic review of human clinical trials of resveratrol covering metabolic, inflammatory and ageing-related endpoints.
Key Findings
Resveratrol showed favourable effects on some metabolic markers but no human trial has demonstrated an effect on lifespan.
Conclusions
Human evidence for resveratrol as a longevity agent remains preclinical and unproven.
Limitations
No trials with mortality endpoints; bioavailability is low and variable.
Supplements Studied
No human trial has demonstrated an effect of resveratrol on lifespan
Outcomes Measured
Resveratrol showed favourable effects on some metabolic markers but no human trial has demonstrated an effect on lifespan
Study Details
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