Metabolism and functional effects of plant-derived omega-3 fatty acids in humans
Baker EJ, Miles EA, Burdge GC, Yaqoob P, Calder PC
Published in Progress in Lipid Research
Methodology
Review of human conversion of alpha-linolenic acid to EPA and DHA and downstream functional effects
Key Findings
Conversion of alpha-linolenic acid to EPA is limited and conversion to DHA is very low in humans
Conclusions
Perilla and other ALA-rich oils are poor substitutes for preformed EPA and DHA
Limitations
Narrative review; conversion estimates vary widely between individuals
Supplements Studied
Conversion of alpha-linolenic acid to EPA is limited and conversion to DHA is very low in humans
Conversion of alpha-linolenic acid to EPA is limited and conversion to DHA is very low in humans
Outcomes Measured
Conversion of alpha-linolenic acid to EPA is limited and conversion to DHA is very low in humans
Study Details
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