What is the efficacy of dietary, nutraceutical, and probiotic interventions for the management of gastroesophageal reflux disease symptoms? A systematic literature review and meta-analysis
Martin Z, Spry G, Hoult J, Maimone IR, Tang X
Published in Clinical Nutrition ESPEN
Methodology
PRISMA systematic review and meta-analysis of dietary, nutraceutical and probiotic interventions for GERD symptoms in adults, searching MEDLINE, CINAHL, CENTRAL and Embase, with Academy Quality Criteria Checklist appraisal and GRADE certainty rating
Key Findings
Evidence for dietary and nutraceutical interventions in GERD is limited and of low certainty, with no intervention demonstrating robust symptom benefit.
Conclusions
Supplement approaches to reflux remain unproven; dietary modification evidence is weak.
Limitations
Few trials per intervention; heterogeneous symptom measures; low certainty of evidence.
Supplements Studied
Intervention studies were eligible if they evaluated the effect of a dietary, nutraceutical, or probiotic intervention on GERD symptoms in adults with a history of GERD or functional dyspepsia.
Related Health Concerns
Study Details
Access Study
Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.