meta_analysis
    2020

    Efficacy and Safety of Mecobalamin on Peripheral Neuropathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    Unknown authors

    Published in Journal of Alternative and Complementary Medicine

    Key Findings

    15 RCTs, 1707 patients; mecobalamin improved clinical therapeutic efficacy but not pain or neuropathic symptom scores; most trials high risk of bias.

    Conclusions

    Methylcobalamin shows modest benefit in peripheral neuropathy, limited by poor trial quality.

    Supplements Studied

    Mecobalamin alone (risk ratio [RR] = 1.17; 95% confidence interval [CI] 1.03-1.33) and mecobalamin in combination (RR = 1.32; 95% CI 1.21-1.45) are more effective than active control.

    Related Health Concerns

    Tingling Sensations
    Peripheral Neuropathy

    Study Details

    Year:2020
    Quality Score:6/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.