meta_analysis
    2022

    Effect of isoflavone supplementation on menopausal symptoms: a systematic review and meta-analysis of randomized controlled trials

    Kang I, Rim CH, Yang HS, Choe JS

    Published in Nutrition Research and Practice

    Methodology

    Systematic review and meta-analysis of 11 randomized controlled trials of isoflavone supplementation (49.3-135 mg/day for 12 weeks to 2 years) on menopausal symptoms and ovarian hormones.

    Key Findings

    Isoflavone supplementation significantly increased estradiol levels and improved the Kupperman index, but heterogeneity was high.

    Conclusions

    Isoflavones may modestly influence climacteric symptoms and hormones; findings require cautious interpretation.

    Limitations

    High statistical heterogeneity; variable doses and durations.

    Related Health Concerns

    Perimenopause

    Study Details

    Year:2022
    Duration:12 weeks
    Quality Score:6/10

    Access Study

    View on DOIView on PubMedOriginal Source

    Disclosures

    Funding

    Not reported

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.