Phytoestrogens for menopausal vasomotor symptoms
Lethaby A, Marjoribanks J, Kronenberg F, Roberts H, Eden J, Brown J
Published in Cochrane Database of Systematic Reviews
Key Findings
Pooled trials of red clover extracts showed no consistent reduction in hot flush frequency compared with placebo, although some genistein-rich preparations did reduce flushes.
Conclusions
Evidence does not show a clear benefit of red clover isoflavones for vasomotor symptoms.
Limitations
Substantial heterogeneity, small trials, high placebo response rates.
Supplements Studied
Pooled trials of red clover extracts showed no consistent reduction in hot flush frequency compared with placebo.
Outcomes Measured
Red clover extracts showed no consistent reduction in hot flush frequency versus placebo.
Related Health Concerns
Study Details
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