The Association between Vitamin D Deficiency and Perinatal Depression: A Systematic Review and Meta-Analysis
Yuan Y, Qu L, Sun Q, He P
Published in Alpha Psychiatry
Methodology
Systematic review and meta-analysis of 13 observational studies relating serum vitamin D levels to prenatal and postpartum depression.
Key Findings
Prenatal depression was associated with lower vitamin D levels (SMD -0.41, 95% CI -0.57 to -0.25); postpartum analyses showed considerable heterogeneity.
Conclusions
Low vitamin D is associated with higher perinatal depression risk, though causality is unproven.
Limitations
Observational studies only; heterogeneity in postpartum analyses; no supplementation outcomes.
Supplements Studied
Reduced vitamin D levels are significantly associated with the incidence of perinatal depression.
Related Health Concerns
Study Details
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Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.