Vitamin D Supplementation for Patients with Dysmenorrhoea: A Meta-Analysis with Trial Sequential Analysis of Randomised Controlled Trials
Lin KC, Huang KJ, Lin MN, Wang CY
Published in Nutrients
Methodology
Meta-analysis with trial sequential analysis of 11 randomised controlled trials of vitamin D supplementation in dysmenorrhoea, with pain intensity as the primary outcome.
Key Findings
Vitamin D supplementation significantly decreased pain intensity versus control, with reduced rescue analgesic use.
Conclusions
Vitamin D appears to reduce dysmenorrhoea pain, though trial sizes are small and heterogeneous.
Limitations
Small included trials, varied dosing regimens, and heterogeneity across primary and secondary dysmenorrhoea.
Supplements Studied
Vitamin D supplementation significantly decreased pain intensity in patients with dysmenorrhoea compared with controls.
Outcomes Measured
Vitamin D supplementation significantly decreased pain intensity in patients with dysmenorrhoea compared with controls (pooled mean difference, -1.64; 95% confidence interval, -2.27 to -1.00).
Related Health Concerns
Study Details
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Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.