meta_analysis
    2019

    Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery: systematic review and meta-analysis of randomized clinical trials

    de la Barrera-Nunez MC, Yanez-Vico RM, Batista-Cruzado A, et al.

    Published in Medicina Oral Patologia Oral y Cirugia Bucal

    Abstract

    Systematic review and meta-analysis of bromelain for outcomes after third molar surgery.

    Key Findings

    Pooled trials showed bromelain reduced postoperative swelling and trismus after third molar surgery, with smaller and less consistent effects on pain.

    Conclusions

    Bromelain appears useful as an adjunct for post-surgical edema.

    Limitations

    Small heterogeneous trials, differing dosing regimens and comparators.

    Supplements Studied

    Bromelain
    Enzyme

    Pooled trials showed bromelain reduced postoperative swelling and trismus after third molar surgery, with smaller and less consistent effects on pain.

    Outcomes Measured

    Pooled trials showed bromelain reduced postoperative swelling and trismus after third molar surgery, with smaller and less consistent effects on pain.

    Study Details

    Year:2019
    Quality Score:6/10

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