rct
    2026
    High Quality

    Efficacy and safety of minocycline in patients with acute ischaemic stroke (EMPHASIS): a multicentre, double-blind, randomised controlled trial

    et al

    Published in Lancet

    Key Findings

    Minocycline given in acute ischaemic stroke was evaluated for neuroprotective effect on functional outcome in a large multicentre trial.

    Conclusions

    Anti-inflammatory neuroprotection remains under active randomised evaluation in acute stroke.

    Limitations

    Recent publication; generalisability beyond trial setting unclear.

    Outcomes Measured

    Cerebral Infarction Volume

    Minocycline was assessed for efficacy and safety in patients with acute ischaemic stroke in a multicentre, double-blind, randomised controlled trial.

    Study Details

    Year:2026
    Quality Score:8/10

    Access Study

    View on DOIView on PubMedOriginal Source

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