Association of glucosamine and chondroitin sulfate with knee osteoarthritis progression: the Osteoarthritis Initiative cohort
Yang W, Sun C, He SQ, Chen JY, Wang Y, Zhuo Q
Published in Journal of Arthroplasty
Methodology
Prospective observational analysis of Osteoarthritis Initiative participants using glucosamine/chondroitin, with 4-year radiographic and symptom follow-up
Key Findings
Supplement users showed no significant difference in joint space narrowing or WOMAC pain progression compared with non-users.
Conclusions
Real-world use of glucosamine/chondroitin was not associated with slowed knee osteoarthritis progression.
Limitations
Observational design; self-reported supplement use and variable formulations.
Supplements Studied
Glucosamine and chondroitin sulfate use was not associated with slowed radiographic or symptomatic progression of knee osteoarthritis.
Supplement users showed no significant difference in joint space narrowing or WOMAC pain progression compared with non-users.
Related Health Concerns
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.