Advances in the mechanism of emodin-induced hepatotoxicity
Wang Y, Zhao M, Li B, Geng X
Published in Heliyon
Methodology
Toxicology evidence synthesis summarising experimental studies on mechanisms of emodin-induced hepatocyte injury
Key Findings
High doses and long-term use of emodin can cause liver toxicity, with mechanisms of hepatocyte injury still incompletely defined.
Conclusions
Safe usage requires dose limits and awareness of hepatotoxic potential.
Limitations
Narrative synthesis; evidence is preclinical; no human dose thresholds established.
Supplements Studied
However, high doses and long-term use of emodin can also lead to liver toxicity. Nevertheless, the mechanism of emodin-induced liver toxicity remains unclear at present.
Related Health Concerns
Study Details
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Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.