Zinc supplementation and T-cell function in older adults: a randomized controlled trial
Prasad AS, Beck FW, Bao B, Fitzgerald JT, Snell DC, Steinberg JD, Cardozo LJ
Published in American Journal of Clinical Nutrition
Methodology
Randomized placebo-controlled trial of zinc gluconate 45 mg/day in older adults measuring infection incidence, plasma zinc and oxidative stress markers.
Key Findings
Zinc-supplemented elderly had significantly fewer infections and lower inflammatory cytokine and oxidative stress markers than placebo.
Conclusions
Zinc restores T-cell mediated immune competence in ageing.
Limitations
Single centre; modest sample.
Supplements Studied
Zinc-supplemented elderly had significantly fewer infections and lower inflammatory cytokine and oxidative stress markers
Outcomes Measured
Zinc-supplemented elderly had significantly fewer infections and lower inflammatory cytokine and oxidative stress markers than placebo
Study Details
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