Centella asiatica in wound healing and scar management: a review of clinical and preclinical evidence
Bylka W, Znajdek-Awizen P, Studzinska-Sroka E, Brzezinska M
Published in Postepy Dermatologii i Alergologii
Methodology
Review of preclinical and small clinical studies of Centella asiatica triterpenes on collagen synthesis and wound healing
Key Findings
Asiaticoside and madecassoside stimulate collagen I synthesis and improved healing in small trials of wounds, hypertrophic scars and striae.
Conclusions
Topical Centella preparations have plausible collagen-mediated benefits for wound and scar healing; oral evidence is weaker.
Limitations
Mostly preclinical or small uncontrolled clinical studies.
Supplements Studied
Asiaticoside and madecassoside from Centella asiatica stimulate type I collagen synthesis and improved healing of wounds and hypertrophic scars.
Outcomes Measured
Asiaticoside and madecassoside stimulate type I collagen synthesis in skin.
Asiaticoside and madecassoside stimulate collagen I synthesis and improved healing in small trials of wounds, hypertrophic scars and striae.
Related Health Concerns
Study Details
Access Study
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.