Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials
Avgerinos KI, Spyrou N, Bougioukas KI, Kapogiannis D
Published in Experimental Gerontology, Vol. 108, pp. 166-173
Methodology
Meta-analysis of randomized controlled trials of creatine supplementation on memory, attention and processing speed in healthy adults.
Key Findings
Creatine improved short-term memory and reasoning, with the largest effects under sleep deprivation or metabolic stress; effects on learning speed in rested young adults were small.
Conclusions
Creatine gives context-dependent cognitive benefits, strongest when brain energy supply is stressed.
Limitations
Few trials; cognitive test batteries differ widely.
Supplements Studied
Creatine improved short-term memory and reasoning, with the largest effects under sleep deprivation or metabolic stress
Outcomes Measured
Creatine improved short-term memory and reasoning, with the largest effects under sleep deprivation or metabolic stress
Creatine improved short-term memory and some reasoning tasks but showed no consistent benefit for reaction time or executive function
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.