The effect of coenzyme Q10 supplementation on in vitro fertilization outcomes in infertile patients with polycystic ovary syndrome
Mutlu Özmen L, İnanç N, Mutlu AE, Çapar AG
Published in Nutr Health, pp. 2601060261491431
Methodology
Retrospective cohort of 154 women with PCOS having IVF: CoQ10 100 mg/day for four weeks beforehand (n = 75) versus none (n = 79).
Key Findings
More MII oocytes; live birth 30.7% vs 6.3% (OR 6.55, 95% CI 2.34-18.34), persisting after adjustment for age and BMI.
Conclusions
Associated with better outcomes; randomized confirmation required.
Limitations
Retrospective and non-randomized; selection bias and confounding by indication cannot be excluded; groups differed in weight.
Supplements Studied
Pre-IVF CoQ10 supplementation was associated with better embryological and reproductive outcomes in this cohort
Related Health Concerns
Study Details
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