A randomized trial of coenzyme Q10 in patients with confirmed statin myopathy
Taylor BA, Lorson L, White CM, Thompson PD
Published in Atherosclerosis, Vol. 238 (2), pp. 329-35
Methodology
Randomized, double-blind, placebo-controlled crossover trial of CoQ10 600 mg/day versus placebo during simvastatin rechallenge in patients with confirmed statin myalgia.
Key Findings
CoQ10 did not reduce muscle pain severity or improve muscle strength during statin therapy compared with placebo.
Conclusions
Coenzyme Q10 supplementation does not relieve statin-associated muscle symptoms.
Limitations
Small sample, short exposure, single statin; only patients with confirmed myalgia included.
Supplements Studied
CoQ10 did not reduce muscle pain severity or improve muscle strength during statin therapy compared with placebo.
Outcomes Measured
CoQ10 did not reduce muscle pain severity or improve muscle strength during statin therapy compared with placebo.
Study Details
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Disclosures
Funding
National Institutes of Health (no manufacturer funding)
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.