Remedy Routes
    rct
    2016

    Effect of coenzyme Q10 plus nicotinamide adenine dinucleotide supplementation on maximum heart rate after exercise testing in chronic fatigue syndrome - A randomized, controlled, double-blind trial

    Castro-Marrero J, Saez-Francas N, Segundo MJ

    Published in Clinical Nutrition, Vol. 35 (4), pp. 826-34

    Key Findings

    CoQ10 plus NADH for eight weeks reduced maximum heart rate during exercise and improved fatigue scores versus placebo.

    Conclusions

    Combination product, so NADH's independent effect is unclear.

    Limitations

    Combination intervention, surrogate endpoints.

    Supplements Studied

    NADH
    Compound

    CoQ10 plus NADH reduced maximum heart rate during exercise and improved fatigue scores versus placebo.

    CoQ10
    Compound

    CoQ10 plus NADH supplementation for 8 weeks is safe and potentially effective in reducing max HR during a cycle ergometer test and also on fatigue in CFS.

    Outcomes Measured

    CoQ10 Synthesis Support

    CoQ10 plus NADH for eight weeks reduced maximum heart rate during exercise and improved fatigue scores versus placebo.

    Related Health Concerns

    Chronic Fatigue Syndrome (ME/CFS)
    Post-Exertional Malaise
    Chronic Fatigue

    Study Details

    Year:2016
    Sample Size:80
    Duration:8 weeks
    Quality Score:6/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.