rct
2005
High Quality
St John's wort for obsessive-compulsive disorder: a double-blind placebo-controlled trial
Kobak KA, Taylor LV, Bystritsky A, Kohlenberg CJ, Greist JH, Tucker P
Published in International Clinical Psychopharmacology
Methodology
Randomized double-blind placebo-controlled trial of standardized Hypericum perforatum extract in adults with obsessive-compulsive disorder.
Key Findings
St John's wort produced no greater symptom reduction than placebo over twelve weeks.
Conclusions
St John's wort is not effective for obsessive thoughts.
Limitations
Modest sample; fixed dose only.
Supplements Studied
St. Johns Wort
Herb
St John's wort produced no greater symptom reduction than placebo over twelve weeks
Outcomes Measured
St John's wort produced no greater symptom reduction than placebo over twelve weeks
Related Health Concerns
Study Details
Year:2005
Sample Size:60
Duration:12 weeks
Quality Score:7/10
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