systematic_review
    2019
    High Quality

    Glutamine supplementation and gut barrier and mucosal immune function: a systematic review

    Perna S, Alalwan TA, Alaali Z, Alnashaba T, Gasparri C, Infantino V

    Published in International Journal of Molecular Sciences

    Methodology

    Systematic review of clinical trials of glutamine supplementation on intestinal permeability, mucosal integrity and immune markers.

    Key Findings

    Glutamine improved intestinal permeability markers in catabolic and stressed patients, with little effect in healthy adults.

    Conclusions

    Glutamine supports mucosal barrier function under physiological stress but not routinely in healthy people.

    Limitations

    Populations heterogeneous; permeability assays vary.

    Supplements Studied

    L-Glutamine
    Amino Acid

    Glutamine improved intestinal permeability markers in catabolic and stressed patients

    Outcomes Measured

    Glutamine improved intestinal permeability markers in catabolic and stressed patients, with little effect in healthy adults

    Glutamine improved intestinal permeability markers in catabolic and stressed patients, with little effect in healthy adults.

    Study Details

    Year:2019
    Duration:4 weeks
    Quality Score:7/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.