Effect of Lactobacillus plantarum on symptoms of irritable bowel syndrome: a randomized trial with a null primary outcome
Sen S, Mullan MM, Parker TJ, Woolner JT, Tarry SA, Hunter JO
Published in Digestive Diseases and Sciences
Methodology
Randomised double-blind placebo-controlled crossover trial of Lactobacillus plantarum 299v in patients with IBS, measuring symptom scores and colonic fermentation
Key Findings
Neither IBS symptom scores nor colonic gas production differed significantly between L. plantarum and placebo.
Conclusions
An early controlled trial found no symptomatic benefit of L. plantarum 299v in IBS.
Limitations
Small sample; short treatment periods; older diagnostic criteria.
Supplements Studied
Neither IBS symptom scores nor colonic gas production differed significantly between L. plantarum and placebo.
Outcomes Measured
Neither IBS symptom scores nor colonic gas production differed significantly between L. plantarum and placebo.
Related Health Concerns
Study Details
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