rct
    2011

    Xylitol nasal irrigation in the management of chronic rhinosinusitis: a pilot study

    Weissman JD, Fernandez F, Hwang PH

    Published in The Laryngoscope

    Methodology

    Prospective randomized double-blinded controlled crossover pilot study of 10-day courses of xylitol versus saline nasal irrigation

    Key Findings

    SNOT-20 fell 2.43 points during xylitol irrigation versus a 3.93-point rise during saline (P = .0437); no difference in visual analogue scores

    Conclusions

    Xylitol irrigation was well tolerated and produced modest symptom improvement in a pilot setting

    Limitations

    Very small pilot, 25% dropout, short duration, only one instrument positive

    Related Health Concerns

    Study Details

    Year:2011
    Sample Size:20
    Duration:3 weeks
    Quality Score:5/10

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