Camelina Sativa Oil, but not Fatty Fish or Lean Fish, Improves Serum Lipid Profile in Subjects with Impaired Glucose Metabolism - A Randomized Controlled Trial
Schwab US, Lankinen MA, de Mello VD, Manninen SM, Kurl S
Published in Molecular Nutrition & Food Research
Abstract
Randomized controlled trial comparing camelina sativa oil, fatty fish and lean fish in impaired glucose metabolism.
Methodology
12-week four-arm randomized controlled trial in 79 adults with impaired fasting glucose (BMI 25-36): camelina sativa oil providing 10 g/day ALA, fatty fish, lean fish, or control diet limited in fish and ALA.
Key Findings
Total and LDL cholesterol fell in the camelina oil group versus both fish groups, and LDL-C/HDL-C and ApoB/ApoA-I ratios fell versus lean fish; no significant changes occurred in glucose metabolism or low-grade inflammation markers.
Conclusions
Camelina oil improved the serum lipid profile relative to fish-enriched diets, but did not change glucose metabolism or inflammation.
Limitations
Modest group sizes (about 20 per arm), single Finnish cohort, surrogate lipid endpoints, no clinical event data.
Supplements Studied
Camelina sativa oil reduced total and LDL cholesterol and the LDL-to-HDL ratio, whereas fatty fish and lean fish did not, in adults with impaired glucose metabolism.
Outcomes Measured
A diet enriched in CSO improves serum lipid profile as compared with a diet enriched in FF or LF in subjects with impaired fasting glucose.
Camelina sativa oil reduced total and LDL cholesterol and the LDL-to-HDL ratio, whereas fatty fish and lean fish did not, in adults with impaired glucose metabolism.
Camelina sativa oil reduced total and LDL cholesterol and the LDL-to-HDL ratio, whereas fatty fish and lean fish did not, in adults with impaired glucose metabolism.
Related Health Concerns
Study Details
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Disclosures
Funding
Academic funding (University of Eastern Finland collaboration)
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