meta_analysis
2024
The safety and efficacy of N-acetylcysteine as an augmentation in the treatment of obsessive-compulsive disorder in adults: a systematic review and meta-analysis of randomized clinical trials
Eghdami S, Eissazade N, Heidari Mokarar M
Published in Frontiers in Psychiatry
Key Findings
Across six RCTs (n=195), NAC augmentation showed a borderline benefit at five to eight weeks only.
Conclusions
NAC augmentation may benefit moderate to severe OCD; larger trials are needed.
Supplements Studied
N-Acetyl Cysteine (NAC)
Amino Acid
Augmentation of NAC with SSRIs may benefit patients with moderate to severe OCD. However, it is necessary to conduct additional multi-center trials over extended periods.
Related Health Concerns
Study Details
Year:2024
Quality Score:6/10
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