rct
    1990
    High Quality

    A randomized, double-blind trial of nystatin therapy for the candidiasis hypersensitivity syndrome

    Dismukes WE, Wade JS, Lee JY

    Published in New England Journal of Medicine

    Methodology

    Randomised double-blind crossover trial of oral and vaginal nystatin versus placebo in women diagnosed with candidiasis hypersensitivity syndrome.

    Key Findings

    Nystatin reduced vaginal symptoms slightly but did not improve systemic symptoms more than placebo, which also produced large improvements.

    Conclusions

    Systemic "candida hypersensitivity" symptoms do not respond specifically to antifungal therapy.

    Limitations

    Small crossover trial; older diagnostic framework.

    Related Health Concerns

    Candida Overgrowth

    Study Details

    Year:1990
    Sample Size:42
    Quality Score:8/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.