systematic_review
    2019
    High Quality

    Omega-3 and omega-6 polyunsaturated fatty acids for dry eye disease

    Downie LE, Ng SM, Lindsley KB, Akpek EK

    Published in Cochrane Database of Systematic Reviews

    Key Findings

    Across 34 RCTs (4314 participants), omega-3 supplementation showed uncertain effects on dry eye symptoms; the largest trial (DREAM) found no benefit over placebo.

    Conclusions

    Evidence for omega-3 supplementation in dry eye disease is of low to moderate certainty.

    Limitations

    High heterogeneity, many small trials at high risk of bias.

    Supplements Studied

    There is uncertainty as to whether omega-3 supplements improve dry eye signs and symptoms.

    Related Health Concerns

    Dry Eyes

    Study Details

    Year:2019
    Sample Size:4,314
    Quality Score:9/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.