Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial
Morishita D, Tomita T
Published in American Journal of Gastroenterology
Methodology
Randomized placebo-controlled trial comparing senna, magnesium oxide and placebo in chronic constipation.
Key Findings
Both magnesium oxide and senna increased complete spontaneous bowel movements versus placebo, with similar efficacy.
Conclusions
Magnesium oxide is as effective as senna for improving bowel movement frequency.
Limitations
Single-country sample; 28-day duration; renal-impaired patients excluded.
Supplements Studied
Magnesium oxide increased complete spontaneous bowel movements versus placebo, comparably to senna
Outcomes Measured
Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial
The response rate for overall improvement was 11.7% in the placebo group, 69.2% in the senna group, and 68.3% in the MgO group (P < 0.0001).
Related Health Concerns
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.