systematic_review
2017
High Quality
Topical capsaicin (high concentration) for chronic neuropathic pain in adults
Derry S, Rice AS, Cole P
Published in Cochrane Database of Systematic Reviews
Methodology
Cochrane review of RCTs of high-concentration topical capsaicin 8% for neuropathic pain.
Key Findings
High-concentration capsaicin gave moderate benefit over low-dose control in postherpetic neuralgia and HIV neuropathy, with application-site burning as the main adverse effect.
Conclusions
Topical capsaicin helps some burning neuropathic pain but itself causes transient burning.
Limitations
Moderate quality evidence; specialist application required.
Related Health Concerns
Study Details
Year:2017
Sample Size:4,665
Quality Score:9/10
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