Sulforaphane treatment of autism spectrum disorder (ASD)
Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW
Published in Proceedings of the National Academy of Sciences
Methodology
Randomized, double-blind, placebo-controlled 18-week trial of sulforaphane-rich broccoli sprout extract in 44 young men with moderate to severe autism.
Key Findings
Aberrant Behavior Checklist and Social Responsiveness Scale scores improved significantly versus placebo, reverting after treatment stopped.
Conclusions
Sulforaphane produced measurable behavioural improvements in autism in this trial.
Limitations
Small, single-centre, males only; behavioural rating scales are subjective.
Supplements Studied
Sulforaphane produced measurable behavioural improvements in autism in this trial.
Related Health Concerns
Study Details
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