Irritable bowel syndrome symptom severity improves equally with probiotic and placebo
Hod K, Sperber AD, Ron Y, Boaz M, Dickman R, Berliner S, Halpern Z, Maharshak N, Dekel R
Published in World Journal of Gastroenterology
Methodology
Randomised double-blind placebo-controlled trial of a multi-strain probiotic including Lactobacillus acidophilus in women with diarrhoea-predominant IBS
Key Findings
Symptom severity improved substantially in both arms with no significant difference between probiotic and placebo.
Conclusions
A large placebo response can fully account for symptom improvement attributed to probiotics in IBS.
Limitations
Women only; single formulation; eight-week duration.
Supplements Studied
Symptom severity improved substantially in both arms with no significant difference between probiotic and placebo.
Outcomes Measured
Symptom severity improved substantially in both arms with no significant difference between probiotic and placebo.
Related Health Concerns
Study Details
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