Effects of iron supplementation on attention deficit hyperactivity disorder in children
Konofal E, Lecendreux M, Deron J, Marchand M, Cortese S, Zaïm M, Mouren MC, Arnulf I
Published in Pediatric Neurology
Methodology
Randomized, double-blind, placebo-controlled pilot trial of oral iron 80 mg/day for 12 weeks in non-anaemic children with ADHD and low serum ferritin.
Key Findings
ADHD Rating Scale scores improved progressively with iron and the change approached but did not reach statistical significance versus placebo; Clinical Global Impression improved significantly.
Conclusions
Iron may benefit ADHD symptoms in children with low ferritin, but the pilot was underpowered.
Limitations
Very small sample; pilot design; primary endpoint not statistically significant.
Supplements Studied
ADHD Rating Scale scores improved with iron in children with low ferritin but did not reach statistical significance versus placebo.
Related Health Concerns
Study Details
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Disclosures
Funding
French academic/hospital funding
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.