Vinpocetine for cognitive impairment and dementia
Szatmári SZ, Whitehouse PJ
Published in Cochrane Database of Systematic Reviews
Methodology
Cochrane systematic review of randomised, double-blind, placebo-controlled trials of vinpocetine in cognitive impairment and dementia.
Key Findings
Three small trials suggested benefit on global cognitive measures, but all predated modern dementia diagnostic criteria and were too small and heterogeneous for reliable conclusions.
Conclusions
The evidence is insufficient to support the use of vinpocetine for dementia; adequately powered modern trials are required.
Limitations
Old trials, outdated diagnostic criteria, small samples, unclear allocation concealment.
Supplements Studied
The evidence is insufficient to support the use of vinpocetine for people with dementia.
Outcomes Measured
Small older trials suggested benefit on global cognitive measures but were insufficient for conclusions.
Related Health Concerns
Study Details
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